I am a Firefox fan-boy... and more than that, a tabbed-browsing junkie. It comes in very handy when working on the
Sloodle project, and I've got our main site's forums open in one tab, alongside documentation, a webmail folder (or 5), and a locally hosted
Moodle site for testing on.
One thing I've learned the
hard way recently though is to be really sure of what tab you're using at what moment. Having tried a few things out in the Sloodle code on my local installation, I wanted to uninstall it from my local Moodle, and re-install it to see if my changes worked properly. Unfortunately, the Moodle tab I had open at the time wasn't the one on my local machine... but rather, the one on my web-server. I didn't realise until a fraction of a second too late!
I didn't lose any seriously important data... this time... but it was quite a nuisance anyway.
I now simply don't keep more than one Moodle open in the same instance of Firefox at the same time. It's not worth the risk!